IOCB Prague

Ivan Rosenberg Group

Nucleotides and Oligonucleotides
Research Group
Distinguished Emeritus
CHEM cluster

About our group

The scientific program of the group is directed towards basic research in the area of nucleoside phosphonic acids (NPAs) as potential antimetabolites, building units for solid phase synthesis of chimeric antisense oligonucleotides as compounds capable of interfering with gene expression, and regulatory oligonucleotides (2’,5’-linked oligoadenylates and CpG oligonucleotides).